Research topics

Novel synthetic methodology

  • novel routes to unnatural amino alcohols and amino acids
  • aminometalation of olefins
  • Lewis acid catalysed allylic substitution reactions
  • instalation of hydroxamic acid functionality
  • dynamic chemistry for drug discovery

Drug discovery

  • drug discovery projects on contract research bases
  • development of rationally designed malarial protease inhibitors
  • development of selective aspartic proteinase inhibitors

Process chemistry

  • development of synthetic routes for large scale synthesis
  • optimization of problematic steps

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