Research topics
Novel synthetic methodology
- novel routes to unnatural amino alcohols and amino acids
- aminometalation of olefins
- Lewis acid catalysed allylic substitution reactions
- instalation of hydroxamic acid functionality
- dynamic chemistry for drug discovery
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Drug discovery
- drug discovery projects on contract research bases
- development of rationally designed malarial protease inhibitors
- development of selective aspartic proteinase inhibitors
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Process chemistry
- development of synthetic routes for large scale synthesis
- optimization of problematic steps
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