94. Diastereoselective C–H Functionalizations

Cizikovs, A.; Basens, E. E.; Zagorska, P. A.; Grigorjeva, L. In Comprehensive Chirality, 2nd edition (Ed. J. R. Cossy). 2023, Accepted for publication Elsevier Inc. DOI:10.1016/B978-0-32-390644-9.00101-3

93. Phenylglycinol Derived Chemistry

Lidumniece, E.; Bolsakova, J.; Grigorjeva, L. In Comprehensive Chirality, 2nd edition (Ed. J. R. Cossy). 2023, Accepted for publication Elsevier Inc. DOI:10.1016/B978-0-32-390644-9.00100-1

91. Asparagusic Acid – A Unique Approach toward Effective Cellular Uptake of Therapeutics: Application, Biological Targets, and Chemical Properties

Nikitjuka, A.; Žalubovskis, R. ChemMedChem, 2023, 18, e202300143. DOI:10.1002/cmdc.202300143

90. Assembling the Methanoindene Cage of Phragmalin-Type Natural Products

Becica, J.; Rāciņš, O.; Ivanova, M.; Jirgensons, A. J. Org. Chem., 2023,  88, 10306–10309. DOI:10.1021/acs.joc.3c00952

89. Synthesis and evaluation of an agrocin 84 toxic moiety (TM84) analogue as a malarial threonyl tRNA synthetase inhibitor

Rodriguez Buitrago, J. A.; Leitis, G.; Kaņepe-Lapsa, I.; Rudnickiha, A.;  Parisini, E.; Jirgensons, A. Org. Biomol. Chem., 2023, 21, 5433-5439. DOI:10.1039/D3OB00670K

88. Co(III) Intermediates in Cobalt-Catalyzed, Bidentate Chelation Assisted C(sp²)-H Functionalizations

Cizikovs, A.; Grigorjeva, L. Inorganics, 2023, 11(5), 194. DOI:10.3390/inorganics11050194

88. 3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitorswman

Bobileva, O.; Bobrovs, R.; Sirma, E. E.; Kanepe, I.; Bula, A. L.; Patetko, L.; Ramata-Stunda, A.; Grinberga, S.; Jirgensons, A.; Jaudzems, K. Molecules, 2023, 28(2), 768. DOI:10.3390/molecules28020768

87. Synthesis and SAR of phenylazoles, active against Staphylococcus aureus Newman

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86. Intramolecular Friedel–Crafts alkylation by electrochemical carbenium ion generation

Lielpētere, A.; Šilaks, A.; Jirgensons, A. Chem. Heterocycl. Compd., 2022, 58, 732-736. DOI:10.1007/s10593-023-03150-w

85. Mechanistic Studies on Cobalt-Catalyzed, Bidentate Chelation-Assisted C-H Bond Functionalization

Lukasevics, L.; Grigorjeva, L. In Handbook of C–H Functionalization, Maiti, D. Ed., Wiley, (2022), In Press. DOI:10.1002/9783527834242.chf0236

84. Subtilisin-like Serine Protease 1 (SUB1) as an Emerging Antimalarial Drug Target: Current Achievements in Inhibitor Discovery

Lidumniece, E.; Withers-Martinez, C.; Hackett, F.; Blackman, M. J.; Jirgensons, A. J. Med. Chem., 2022, 65, 12535-12545. DOI:10.1021/acs.jmedchem.2c01093

83. Cobalt-catalyzed C(sp²)–H bond imination of phenylalanine derivatives

Lukasevics, L.; Cizikovs, A.; Grigorjeva, L. Chem. Commun., 2022, 58, 9754-9757. DOI:10.1039/D2CC02334B

82. Iron-Catalyzed Fluoromethylene Transfer from a Sulfonium Reagent

Sperga, A.; Zacs, D.; Veliks, J. Org. Lett., 2022, 24, 4474–4478. DOI:10.1021/acs.orglett.2c01757

81. Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1N-(6-Methylpyridyl-2-methyl) Protecting Group

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80. Convergent biomimetic semisynthesis of disesquiterpenoid rumphellolide J

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79. Localising individual atoms of tryptophan side chains in the metallo-β-lactamase IMP-1 by pseudocontact shifts from paramagnetic lanthanoid tags at multiple sites

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78. Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials

Bobrovs, R.; Basens, E. E.; Drunka, L.; Kanepe, I.; Matisone, S.; Velins, K. K.; Andrianov, V.; Leitis, G.; Zelencova-Gopejenko, D.; Rasina, D.; Jirgensons, A.; Jaudzems, K. J. Chem. Inf. Model., 2022, 62, 3263–3273. DOI:10.1021/acs.jcim.2c00422

77. Functionalization of 1N-Protected Tetrazoles by Deprotonation with the Turbo Grignard Reagent

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76. Synthesis of fluorinated leucines, valines and alanines for use in protein NMR

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75. Discovery of sars-cov-2 nsp14 and nsp16 methyltransferase inhibitors by high-throughput virtual screening

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74. C–H bond functionalization by high-valent cobalt catalysis: current progress, challenges and future perspectives

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73. Torii-Type Electrosynthesis of α,β-Unsaturated Esters from Furfurylated Ethylene Glycols and Amino Alcohols

Darzina, M.; Lielpetere, A.; Jirgensons, A. Eur. J. Org. Chem., 2021, 2021, 4224. DOI:10.1002/ejoc.202100605

72. Synthetic Applications of Monofluoromethylsulfonium Salts

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71. Cobalt-Catalyzed C–H Bond Functionalization Using Traceless Directing Group

Cizikovs, A.; Lukasevics, L.; Grigorjeva, L. Tetrahedron 2021, 93, 132307. DOI:10.1016/j.tet.2021.132307

70. Cobalt-Catalyzed Picolinamide-Directed Synthesis of Heterocycles

Lukasevics, L.; Grigorjeva, L. Targets Heterocycl. Syst. (book series) 2021, 25, 144-161. DOI:10.17374/targets.2022.25.144

69. Synthesis of Indazoles From 2-Formylphenylboronic Acids

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68. Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate

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67. Synthesis of ¹³C/¹⁹F/²H labeled indoles for use as tryptophan precursors for protein NMR spectroscopy

Maleckis, A.; Herath, I. D.; Otting, G. Org. Biomol. Chem., 2021, 19, 5133-5147. DOI:10.1039/D1OB00611H

66. Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1

Lidumniece, E.; Withers-Martinez, C.; Hackett, F.; Collins, C. R.; Perrin, A. J.; Koussis, K.; Bisson, C.; Blackman, M. J.; Jirgensons, A. Proc. Natl. Acad. Sci. U.S.A., 2021, 118, e2022696118. DOI:10.1073/pnas.2022696118

65. Sulfonium, (Fluoromethyl)phenyl(2,3,4,5-tetramethylphenyl)-, Tetrafluoroborate(1-) (1:1)

Melngaile, R.; Veliks, J. G. Encycl. Reagents Org. Synth., 2021, pp 1-4. DOI:10.1002/047084289X.rn02379

64. Cobalt-Catalyzed C(sp²)–H Carbonylation of Amino Acids Using Picolinamide as a Traceless Directing Group

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63. Monofluorinated 5-membered rings via fluoromethylene transfer: synthesis of monofluorinated isoxazoline N-oxides

Sperga, A.; Kazia, A.; Veliks, J. Org. Biomol. Chem., 2021, 19, 2688-2691. DOI:10.1039/D1OB00270H

62. Synthesis of 1,2-Dihydroisoquinoline-1-Carboxylates Under Cobalt Catalysis

Zagorska, P. A.; Grigorjeva, L.; Bolsakova, J. Chem. Heterocycl. Compd., 2021, 57(2), 159-165. DOI:10.1007/s10593-021-02888-5

61. Residual Solvent Signal of CDCl₃ as a qNMR Internal Standard for Application in Organic Chemistry Laboratory

Muhamadejev, R.; Melngaile, R.; Paegle, P.; Zibarte, I.; Petrova, M.; Jaudzems, K.; Veliks, J. J. Org. Chem., 2021, 86, 3890-3896. DOI:10.1021/acs.joc.0c02744

60. Optimized Monofluoromethylsulfonium Reagents for Fluoromethylene-Transfer Chemistry

Sperga, A.; Melngaile, R.; Kazia, A.; Belyakov, S.; Veliks, J. J. Org. Chem., 2021, 86, 3196–3212. DOI:10.1021/acs.joc.0c02561

59. Cell‐Free Synthesis of Selenoproteins in High Yield and Purity for Selective Protein Tagging

Welegedara, A. P.; Maleckis, A.; Bandara, R.; Mahawaththa, M. C.; Herath, I. D.; Tan, Y. J.; Giannoulis, A.; Goldfarb, D.; Otting, G.; Huber, T. ChemBioChem, 2021, 22, 1480-1486. DOI:10.1002/cbic.202000785

58. trans-Fluorine Effect in Cyclopropane: Diastereoselective Synthesis of Fluorocyclopropyl Cabozantinib Analogs

Veliks, J.; Videja, M.; Kinens, A.; Bobrovs, R.; Priede, M., Kuka, J. ACS Med. Chem. Lett., 2020, 11(11), 2146-2150. DOI:10.1021/acsmedchemlett.0c00220

57. Cobalt-Catalyzed Carbonylation of The C–H Bond

Lukasvics, L.; Grigorjeva, L., Org. Biomol. Chem., 2020, 18, 7460-7466. DOI:10.1039/D0OB01633K

56. Friedel–Crafts Alkylation with Carbenium Ions Generated by Electrochemical Oxidation of Stannylmethyl Ethers

Lielpetere, A.; Jirgensons, A., Eur. J. Org. Chem., 2020, 29, 4510-4516. DOI:10.1002/ejoc.202000568

55. 2-Aminoquinazolines by Chan–Evans–Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids

Solomin, V. V.; Seins, A.; Jirgensons, A., Synlett, 2020, 31, 1507-1510. DOI:10.1055/s-0040-1707080

54. Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency

Rasina, D.; Stakanovs, G.; Kanepe-Lapsa, I.; Bobrovs, R.; Jirgensons, A., Chem. Heterocycl. Compd., 2020, 56, 786-792. DOI:10.1007/s10593-020-02731-3

53. A Concise Bioinspired Semisynthesis of Rumphellaones A–C and Their C-8 Epimers from β-Caryophyllene

Stakanovs, G.; Mishnev, A.; Rasina, D.; Jirgensons, A., J. Nat. Prod. 2020, 83, 6, 2004-2009. DOI:10.1021/acs.jnatprod.0c00403

52. Synthesis of 3-Hydroxymethyl Isoindolinones via Cobalt-Catalyzed C(sp²)–H Carbonylation of Phenylglycinol Derivatives

Lukasevics, L.; Cizikovs, A.; Grigorjeva, L., Org. Lett. 2020, 22, 2720-2723. DOI:10.1021/acs.orglett.0c00672

51. Cobalt-Catalyzed, Directed C–H Functionalization/Annulation of Phenylglycinol Derivatives with Alkynes

Bolsakova, J.; Lukasevics, L.; Grigorjeva, L., J. Org. Chem. 2020, 85, 4482-4499. DOI:10.1021/acs.joc.0c00207

50. Johnson–Corey–Chaykovsky Fluorocyclopropanation of Double Activated Alkenes: Scope and Limitations

Kazia, A.; Melngaile, R.; Mishnev, A.; Veliks, J. Org. Biomol. Chem. 2020, 18, 1384-1388. DOI:10.1039/C9OB02712B

49. Diastereoselective Monofluorocyclopropanation Using Fluoromethylsulfonium Salts

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48. Exploiting Structural Dynamics to Design Open-Flap Inhibitors of Malarial Aspartic Proteases

Bobrovs, R.; Jaudzems, K.; Jirgensons, A. J. Med. Chem., 2019, 62, 20, 8931-8950. DOI:10.1021/acs.jmedchem.9b00184

47. Fluoromethylene Transfer from Diarylfluoromethylsulfonium Salts: Synthesis of Fluorinated Epoxides

Veliks, J.; Kazia, A. Chem. Eur. J., 2019, 25, 3786 –3789. DOI:10.1002/chem.201900349

46. A Novel Collaborative Approach to Facilitate Chemical Biology

Brennecke, P.; Rasina, D.; Aubi, O.; Herzog, K.; Landskron, J.; Cautain, B.; Vicente, F.; Quintana, J.; Mestres, J.; Stechmann, B.; Ellinger, B.; Brea, J; Kolanowski, J. L.; Pilarski, R.; Orzaez, M.; Pineda-Lucena, A.; Laraia, L.; Nami, F.; Zielenkiewicz, P.; Paruch, K.; Hansen, E.; Von Kries, J. P.; Neuenschwander, M.; Specker, E.; Bartunek, P.; Simova, S.; Leśnikowski, Z.; Krauss, S.; Lehtiö, L.; Bilitewski, U.; Brönstrup, M.; Taskén, K.; Jirgensons, A.; Lickert, H.; Clausen, M. H.; Andersen, J. H.; Vicent, M. J.; Genilloud, O.; Martinez, A.; Nazaré, M.; Fecke, W.; Gribbon, P.
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45. Amination of Carbenium Ions Generated by Directed Protonolysis of Cyclopropane

Skvorcova, M.; Lukasevics, T. L.; Jirgensons, A. J. Org. Chem., 2019,  84, 3780-3792. DOI:10.1021/acs.joc.8b02576

44. Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity Against Cathepsin D

Zogota, R.; Kinena, L.; Withers-Martinez, C.; Blackman, M. J.; Bobrovs, R.; Pantelejevs, T.; Kanepe-Lapsa, I.; Ozola, V.; Jaudzems, K.; Suna, E.; Jirgensons, A. Eur. J. Med. Chem., 2019, 163, 344-352. DOI:10.1016/j.ejmech.2018.11.068

43. Refining the Structure−Activity Relationships of 2-Phenylcyclopropane Carboxylic Acids as Inhibitors of O-Acetylserine Sulfhydrylase Isoforms

Magalhães, J.; Franko, N.; Annunziato, G.; Pieroni, M.; Benoni, R.; Nikitjuka, A.; Mozzarelli, A.; Bettati, S.; Karawajczyk, A.; Jirgensons, A.; Campanini, B.; Costantino, G. J. Enzyme Inhib. Med. Chem., 2019, 34, 31-43. DOI:10.1080/14756366.2018.1518959

42. Azole-Based Non-Peptidomimetic Plasmepsin Inhibitors

Kinena, L.; Leitis, G.; Kanepe-Lapsa, I.; Bobrovs, R.; Jaudzems, K.; Ozola, V.; Suna, E., Jirgensons, A. Arch. Pharm. Chem. Life Sci., 2018, 351, 1800151. DOI:10.1002/ardp.201800151

41. 2-Aminoquinazolin-4(3H)-one Based Plasmepsin Inhibitors with Improved Hydrophilicity and Selectivity

Rasina, D.; Stakanovs, G.; Borysov, O.V.; Pantelejevs, T.; Bobrovs, R.; Kanepe-Lapsa, I.; Tars, K.; Jaudzems, K.; Jirgensons, A. Biorg. Med. Chem., 2018, 26(9), 2488-2500. DOI:10.1016/j.bmc.2018.04.012

40. N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors

Charlton, M.H.; Aleksis, R.; Saint-Leger, A.; Gupta, A; Loza, E.; , Ribas De Pouplana, L.;  Kaula, I.;  Gustina, D.; Madre, M.; Lola, D;  Jaudzems, K.;  Edmund, G.; Randall, C.P.; Kime, L.;  O’Neill, A.J.; Goessens, W.; Jirgensons, A.; Finn, P.W.  ACS Med. Chem. Lett.  2018, 9(2), 84-88. DOI:10.1021/acsmedchemlett.7b00374

39. Carbenium Ion Formation by Fragmentation of Electrochemically Generated Oxonium Ions

Lielpetere, A.; Jirgensons, A. Org. Biomol. Chem., 2018, 16, 5094-5096. DOI:10.1039/c8ob01339j

38. Inhibition of O-Acetylserine Sulfhydrylase by Fluoroalanine Derivatives

Franko, N.; Grammatoglou, K.; Campanini, B.; Costantino, G.; Jirgensons, A.; Mozzarelli, A. J. Enzyme Inhib. Med. Chem., 2018, 33, 1343-1351. DOI:10.1080/14756366.2018.1504040

37. Discovery of Novel Fragments Inhibiting O-Acetylserine Sulphhydrylase by Combining Scaffold Hopping and Ligand–Based Drug Design

Magalhães, J.; Franko, N.; Annunziato, G.; Welch, M.; Dolan, S. K.; Bruno, A.; Mozzarelli, A.; Armao, S.; Jirgensons, A.; Pieroni, M.; Costantino, G.; Campanini, B. J. Enzyme Inhib. Med. Chem., 2018, 33, 1444-1452. DOI:10.1080/14756366.2018.1512596

36. The Ritter Reaction for the Synthesis of Heterocycles (Minireview)

Bolsakova, J.; Jirgensons, A. Chem. Heterocycl. Compd., 2017, 53(11), 1167-1177. DOI:10.1007/s10593-018-2189-y

35. 1-Amino-1-hydroxymethylcyclobutane Derivatives via Intramolecular Amination of Nonclassical Cyclopropylmethyl Cation

Skvorcova, M., Grigorjeva, L., Jirgensons, A. Chem. Heterocycl. Compd., 2017, 53(9), 989-996. DOI:10.1007/s10593-017-2162-1

34. Amide-Group-Directed Protonolysis of Cyclopropane: An Approach to 2,2-Disubstituted Pyrrolidines

Skvorcova, M.; Jirgensons, A. Org. Lett., 2017, 19, 2478-2481. DOI:10.1021/acs.orglett.7b00584

33. N-Sulfonylcarboxamide as an Oxidizing Directing Group for Ruthenium-Catalyzed C–H Activation/Annulation

Petrova, E.; Rasina, D.;  Jirgensons, A. Eur. J. Org. Chem., 2017, 1773-1779. DOI:10.1002/ejoc.201601582

32. Intramolecular Cyclopropylmethylation via Non-Classical Carbocations

Skvorcova, M.; Jirgensons, A. Org. Biomol. Chem., 2017, 15, 6909-6912. DOI:10.1039/C7OB01721A

31. C-Quaternary Alkynyl Glycinols via the Ritter Reaction of Cobalt Complexed Alkynyl Glycols

Grammatoglou, K.; Bolsakova, J.; Jirgensons, A. RSC Adv., 2017, 7, 27530-27537. DOI:10.1039/C7RA03965D

30. Allylic Amination via Acid Catalyzed Leaving Group Activation

Skvorcova, M.; Jirgensons, A. Curr. Green Chem., 2016, 3(2), 145-159. DOI:10.2174/2213346103666160905101423

29. Evaluation of the Characteristics of Leucyl-tRNA Synthetase (LeuRS) Inhibitor AN3365 in Combination with Different Antibiotic Classes

Monteferrante, C.G.; Jirgensons, A.; Varik, V. et al. Eur. J. Clin. Microbiol. Infect. Dis., 2016, 35, 1857-1864. DOI:10.1007/s10096-016-2738-1

28. Targeting Multiple Aminoacyl-tRNA Synthetases Overcomes the Resistance Liabilities Associated with Antibacterial Inhibitors Acting on a Single Such Enzyme

Randall, C.; Rasina, D.; Jirgensons, A.; O’Neill, A. Antimicrob. Agents Chemother., 2016, 60(10) 6359-6361. DOI:10.1128/AAC.00674-16

27. Crystal Structure of Plasmodium Falciparum Proplasmepsin IV: the Plasticity of Proplasmepsins

Recacha, R.; Jaudzems, K.; Akopjana, I.; Jirgensons, A.; Tars, K.
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26. A Polymorphism in LeuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus Aureus

Gupta, A.; Monteferrante, C.; Rasina, D.; Leitis, G.; Randall, C. P.; Tomlinson, J. H.; Jirgensons, A.; Goessens, W.H.F.; Hays, J.P.; O’Neill, A.J.
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25. Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones as Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV

Rasina, D.;  Otikovs, M.; Leitans, J; . Recacha, R.; Borysov, O.V.;  Kanepe-Lapsa, I.; Domraceva, I.; Pantelejevs, T.;  Tars, K.;  Blackman, M.J.; Jaudzems, K.;  Jirgensons,  A. J. Med. Chem., 2016, 59, 374–387. DOI:10.1021/acs.jmedchem.5b01558

24. Synthesis of α‐Ethynyl Glycines (Microreview)

Bolsakova, J.; Jirgensons, A. Eur. J. Org. Chem., 2016, 27, 4591-4602. DOI:10.1002/ejoc.201600253

23. Synthesis of Alkynyl‐Glycinols by Lewis Acid Catalyzed Propargylic Substitution of Bis‐Imidates

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22. Synthesis and Biological Evaluation of Aziridin-1-yl Oxime-based Vorinostat Analogs as Anticancer Agents

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21. Tetrahydro-1,3-oxazepines via Intramolecular Amination of Cyclopropylmethyl Cation

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20. 2-Vinyl Threoninol Derivatives via Acid-Catalyzed Allylic Substitution of Bisimidates

Kumar, V.; Klimovica, K.;  Rasina, D. Jirgensons A. J. Org. Chem., 2015, 80, 5934–5943. DOI:10.1021/acs.joc.5b00529

19. Unsaturated syn– and anti-1,2-Amino Alcohols by Cyclization of Allylic Bis-trichloroacetimidates. Stereoselectivity Dependence on Substrate Configuration

Grigorjeva, L;  Kinens, A.; Jirgensons, A. J. Org. Chem., 2015, 80, 920–927. DOI:10.1021/jo502404y

18. Quinoxaline Based Inhibitors of Malarial Protease PfSUB

Kher, S.S.; Penzo, M.; Fulle, S.; Ebejer,  J.P.;  Finn, P.W. ; Blackman, M.J.; Jirgensons, A. Chem. Heterocycl. Compd., 2015, 50, 1457-1463. DOI:10.1007/s10593-014-1610-4

17. Structures of Plasmepsin II from Plasmodium Falciparum in Complex with Two Hydroxyethylamine-Based Inhibitors

Recacha R.; Leitans J.; Akopjana I.; Aprupe L.; Trapencieris P.; Jaudzems K.; Jirgensons A.; Tars K. Acta Cryst. 2015. F71, 1531-1539. DOI:10.1107/S2053230X15022049

16. Methylprenyl and Prenyl Protection for Sulfonamides

Nikitjuka, A.;  Nekrasova, A.; Jirgensons A. Synlett, 2015,  26, 183-186. DOI:10.1055/s-0034-1379428

15. Substrate Derived Peptidic α-Ketoamides as Inhibitors of the Malarial Protease PfSUB1

Kher, S.S.; Penzo, M.; Fulle, S.; Finn, P.W. ; Blackman, M.J.; Jirgensons, A. Bioorg. Med. Chem. Lett.,  2014, 24(18), 4486-4489. DOI:10.1016/j.bmcl.2014.07.086

14. Semisynthesis of Libiguin A and Its Analogues by Trans-Lactonization of Phragmalin

Grigorjeva, L.; Liepinsh, E.; Razafimahefa, S.; Yahorau, A.; Yahorava, S.; Rasoanaivo, P.; Jirgensons, A.; Wikberg, J.E.S. J. Org. Chem., 2014, 79(9), 4148–4153. DOI:10.1021/jo500318w

13. Plasmepsin Inhibitory Activity and Structure-Guided Optimization of a Potent Hydroxyethylamine-Based Antimalarial Hit

Jaudzems, K.; Tars, K.; Maurops, G.; Ivdra, N; Otikovs, M. ; Leitans, J.; Kanepe-Lapsa, I.; Domraceva, I.; Mutule, I.; Trapencieris, P.; Blackman, M.J.; Jirgensons, A. ACS Med. Chem. Lett., 2014, 5(4), 373–377. DOI:10.1021/ml4004952

12. Synthesis of β-Amino-α-ketoamides (Review)

Kher, S.S.; Jirgensons, A. Curr. Org. Chem., 2014, 18, 2240-2269. DOI:10.2174/1385272819666140818223225

11. Synthesis, Chemical and Biological Properties of Aziridine-1-carbaldehyde Oximes (Minireview)

Nikitjuka, A.; Jirgensons, A. Chem. Heterocycl. Compd., 2014, 49, 1544-1559. Dedicated to Professor Janis Stradins on the occasion of his 80 anniversary. DOI:10.1007/s10593-014-1407-5

10. Unsaturated Amino Alcohols via Cyclization of Allylic Bistrichloroacetimidates

Jirgensons, A.; Grigorjeva, L.; Maleckis, A.; Klimovica, K. Synlett, 2013, 24(18), 2345-2349. DOI:10.1055/s-0033-1338977

9. Synthesis of 5-Substituted 3-Mercapto-1,2,4-Triazoles via Suzuki–Miyaura Reaction

Katkevica, S.; Salun, P.; Jirgensons, A. Tetrahedron Lett., 2013, 54, 4524–4525. DOI:10.1016/j.tetlet.2013.06.067

8. Synthesis of Hydroxamic Acids by Using the Acid Labile O-2-Methylprenyl Protecting Group

Nikitjuka, A; Jirgensons, A. Synlett, 2012, 23, 2972-2974. DOI:10.1055/s-0032-1317687

7. Synthesis of Cyclic N-Tosyl-iminocarbonates by Lewis Acid Catalysed Allylic Substitution of Trichloroacetimidates

Grigorjeva, L.; Jirgensons, A. Eur. J. Org. Chem., 2012, 27, 5307–5316. DOI:10.1002/ejoc.201200378

6. Plasmodium Subtilisin-like Protease 1 (SUB1): Insights into the Active-Site Structure, Specificity and Function of a Pan-Malaria Drug Target

Withers-Martinez, C.; Suarez, C.; Fulle, S.; Kher, S.; Penzo, M.; Ebejer, J.-P.; Koussis, K.; Hackett, F.; Jirgensons, A.; Finn, P.; Blackman, M.J. Int. J. Parasitol., 2012, 42, 597-612. DOI:10.1016/j.ijpara.2012.04.005

5. Novel Synthesis of 2-Trichloromethyl-4-vinyl-oxazoline and its Derivatization by Ring Cleavage Reactions

Grigorjeva, L.; Maleckis, A.; Klimovica, K.; Skvorcova, M.; Ivdra, N.; Leitis, G.; Jirgensons, A. Chem. Heterocycl. Compd., 2012, 48, 919-924. Dedicated to professor Ivars Kalvinsh on the occasion of his 65th birthday. DOI:10.1007/s10593-012-1077-0

4. C-Quaternary Vinylglycinols by Metal Catalysed Cyclization of Allylic Bis-Trichloroacetimidates

Klimovica, K.; Grigorjeva, L.; Maleckis, A.; Popelis, J.; Jirgensons, A. Synlett, 2011, 2849-2851. DOI:10.1055/s-0031-1289537

3. Lewis Acid Catalyzed Intramolecular Allylic Substitution of Bis(trichloroacetimidates): A Versatile Approach to Racemic Unsaturated Amino Acids

Grigorjeva, L.; Jirgensons, A. Eur. J. Org. Chem., 2011, 2421–2425. DOI:10.1002/ejoc.201100060

2. Catalytic Enantioselective Synthesis of 4-Vinyl-2-Trichloromethyloxazoline: An Access to Enantioenriched Vinylglycinol Surrogate

Maleckis, A.; Klimovica, K.; Jirgensons, A. J. Org. Chem., 2010, 75, 7897-7900. DOI:10.1021/jo101781y

1. Synthesis of Hydroxamic Acids by Activation of Carboxylic Acids with N,N’-Carbonyldiimidazole: Exploring the Efficiency of the Method

Usachova, N.; Leitis, G.; Jirgensons, A.; Kalvinsh I. Synthetic Comm., 2010, 40, 927–935. DOI:10.1080/00397910903026723

Patents

7. 2-Amino-n-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use.

Jirgensons A., Finn P. W., Edmund G., Skvorcova M., Veliks J., Charlton M. H., Grigorjeva L. Patent N^o WO2021123237, A1, 2021.

6. 2-Amino-n-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use.

Edmund G., Charlton M. H., Finn P. W., Jirgensons A., Skvorcova M., Veliks J., Grigorjeva L. Patent N^o EP4077289, A1, 2020.

5. Novel Compounds, Their Manufacture and Uses (II)

Wikberg, J.; Jirgensons A., Liepinsh E. Patent N^o WO2013110744, A2, 01.08. 2013.

4. Method for Preparing Neramexane or a Salt Thereof

Gold M.R.; Kauss V.; Jirgensons A; Patent N^o WO2011035924, A1, 31. 03. 2011.

3. Method for Producing Memantine

Gold, M.R.; Jirgensons, A; Huber, F.A.M. Patent N^o WO 2010/069555, A1, 24. 06. 2010.

2. Enantioselektīva 2-trihlormetil-4-viniloksazolīna iegūšana

Maleckis, A.; Jirgensons, A. LV Patent Application N^o, P-09-77. 2009.

1. Bicyclosulfonyl Acid (BCSA) Compounds and Their Use as Therapheutic Agents

Finn, P; Robinson, D.; Kham, N.; Jirgensons, A.; Leitis, G.; Kalvinsh I. PCT /GB2008/001683, 16.05.2008.